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Mouse Anti-JSRP1 Recombinant Antibody (6A9) (CBMAB-0249-WJ)

This product is a mouse antibody that recognizes JSRP1. The antibody 6A9 can be used for immunoassay techniques such as: ELISA, WB.
See all JSRP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6A9
Antibody Isotype
IgG2a, Κ
Application
ELISA, WB

Basic Information

Immunogen
JSRP1 (amino acid 1-100) paratial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, Κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
junctional sarcoplasmic reticulum protein 1
Introduction
JSRP1 (Junctional Sarcoplasmic Reticulum Protein 1) encodes the protein which is involved in excitation-contraction coupling at the sarcoplasmic reticulum.
Entrez Gene ID
UniProt ID
Alternative Names
JP45; JP-45
Function
Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity.
Biological Process
Regulation of ryanodine-sensitive calcium-release channel activityManual Assertion Based On ExperimentIBA:GO_Central
Skeletal muscle contractionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Sarcoplasmic reticulum membrane; Endoplasmic reticulum membrane. Colocalizes with ryanodine receptors at the sarcoplasmic reticulum triad membranes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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