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  • Rabbit Anti-PRKAR1B Recombinant Antibody (EG1737)

Rabbit Anti-PRKAR1B Recombinant Antibody (EG1737) (CBMAB-EN2075-LY)

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Datasheet
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Basic Information

Host Animal
Rabbit
Clone
EG1737
Application
WB: 1:500~1:1000 ELISA: 1:20000
Immunogen
The antibody was produced against synthesized peptide derived from internal of human KAP1.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
protein kinase cAMP-dependent type I regulatory subunit beta
Introduction
The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene.
Entrez Gene ID
Human5575
Mouse19085
Rat25521
UniProt ID
HumanP31321
MouseP12849
RatP81377
Alternative Names
REVIEWED
Function
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Biological Process
Learning or memoryIEA:Ensembl
Negative regulation of cAMP-dependent protein kinase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of excitatory postsynaptic potentialIEA:Ensembl
Positive regulation of fear responseIEA:Ensembl
Positive regulation of long-term synaptic potentiationIEA:Ensembl
Positive regulation of sensory perception of painIEA:Ensembl
Protein phosphorylation1 PublicationNAS:UniProtKB
Regulation of synaptic vesicle cycleIEA:Ensembl
Cellular Location
Cell membrane
PTM
The pseudophosphorylation site binds to the substrate-binding region of the catalytic chain, resulting in the inhibition of its activity.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-PRKAR1B Recombinant Antibody (1B4) (CAT#: CBMAB-P2810-YC)

Mouse Anti-PRKAR1B Recombinant Antibody (2A3) (CAT#: CBMAB-P2811-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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