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Mouse Anti-KBTBD8 Recombinant Antibody (7G8A6) (CBMAB-K0046-LY)

This product is antibody recognizes KBTBD8. The antibody 7G8A6 immunoassay techniques such as: WB, FC, IHC, ICC.
Host Species
Mouse
Application
WB, FC, IHC, ICC
Immunogen
Purified recombinant fragment of human KBTBD8 (AA: 264-464) expressed in E. Coli
Antibody Isotype
IgG
Specificity
Human
Clone
7G8A6
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832). The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).
Alternative Name
Kelch Repeat And BTB Domain Containing 8; T-Cell Activation Kelch Repeat Protein; Kelch Repeat And BTB (POZ) Domain Containing 8; TA-KRP; TAKRP; Kelch Repeat And BTB Domain-Containing Protein 8; KIAA1842;
Entrez Gene ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-K0046-LY
Conjugates
Size
Price $
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Second antibody and isotype control