Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238)


See all KBTBD8 antibodies
Online Inquiry
Tested Data
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in ELISA
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in ELISA
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in WB
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in WB
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in WB
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in WB
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in WB
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in WB
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in FC
Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430) (V2LY-0625-LY238) in FC

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT3430
Antibody Isotype
IgG1
Application
WB, FC

Basic Information

Immunogen
Purified recombinant fragment of human KBTBD8 (AA: 264-464) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
84541
UniProt ID
Q8NFY9
Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832).
The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).
Biological Process
Neural crest cell developmentManual Assertion Based On ExperimentIMP:UniProtKB
Neural crest formationManual Assertion Based On ExperimentIMP:UniProtKB
Protein monoubiquitinationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of translationIEA:UniProtKB-KW
Cellular Location
Cytoplasm, cytoskeleton, spindle; Golgi apparatus. Translocates to the spindle apparatus during mitosis.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KBTBD8 Recombinant Antibody (CBT3430)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry