Sign in or Register
  • Home
  • KERA
  • Mouse Anti-KERA Recombinant Antibody (13A204)

Mouse Anti-KERA Recombinant Antibody (13A204) (CBMAB-K0779-LY)

See all KERA antibodies
Go to compare Compare Online Inquiry
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
13A204
Application
IHC, WB
Specificity
Cattle
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.05% sodium azide
Concentration
0.5 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Keratocan
Introduction
The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).[provided by RefSeq, May 2010]
Entrez Gene ID
280785
UniProt ID
O62702
Function
May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.
Biological Process
Cornea development in camera-type eyeIEA:Ensembl
Response to stimulusIEA:UniProtKB-KW
Visual perceptionIEA:UniProtKB-KW
Cellular Location
Secreted, extracellular space, extracellular matrix
Involvement in disease
Cornea plana 2, autosomal recessive (CNA2):
A severe form of cornea plana, a rare ocular disorder characterized by flattened corneal curvature leading to a decrease in refraction, reduced visual activity, hyperopia, hazy corneal limbus, opacities in the corneal parenchyma, and marked arcus senilis often detected at an early age. CNA2 patients manifest extreme hyperopia and additional ocular anomalies such as malformations of the iris, a slit-like pupil, and adhesions between iris and cornea.
PTM
Binds keratan sulfate chains.

Gao, H., Qian, R., Ren, Q., Zhang, L., Qin, W., Zhou, C., ... & Zhang, Y. (2023). The upregulation of keratocan promotes the progression of human pancreatic cancer. Molecular & Cellular Toxicology, 1-10.

Huang, C., Long, X., Peng, C., Lin, P., Tan, H., Lv, W., & Wu, L. (2019). Novel variants in the KERA gene cause autosomal recessive cornea plana in a Chinese family: A case report. Molecular Medicine Reports, 19(6), 4711-4718.

Khan, A. O. (2018). Corneal ectasia in a boy with homozygous KERA mutation. Ophthalmic Genetics, 39(1), 141-143.

Su, T., Chen, X., Liao, X., Wan, Z., Li, Y., Kao, W. W., ... & Liu, Z. (2018). Identification of the function of keratocan positive keratocytes. Investigative Ophthalmology & Visual Science, 59(9), 534-534.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KERA Recombinant Antibody (13A204)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-KERA Recombinant Antibody (Ker-1) (CAT#: CBMAB-K0780-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry