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Mouse Anti-KLK1 Recombinant Antibody (20E7-B7) (CBMAB-P0426-YC)

Provided herein is a Mouse monoclonal antibody against Human Kallikrein 1. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all KLK1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
20E7-B7
Antibody Isotype
IgG2b
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid / Frozen
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
kallikrein 1
Introduction
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
Entrez Gene ID
3816
UniProt ID
P06870
Alternative Names
KLKR; hK1; Klk6
Function
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Biological Process
Regulation of systemic arterial blood pressureManual Assertion Based On ExperimentIBA:GO_Central
Zymogen activationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Extracellular exosome
Nucleus
Secretory granule
PTM
The O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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