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Mouse Anti-KLRF1 Recombinant Antibody (5D12) (CBMAB-N0052-WJ)

This product is a Mouse antibody that recognizes KLRF1. The antibody 5D12 can be used for immunoassay techniques such as: FC, IP, BL.
See all KLRF1 antibodies
Published Data
Fig.1 Representative flow cytometry of the expression of NKp46, CD56 and NKp80 on the surface of human resting NK cells.
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Fig.2 NKp80-dependent stimulation of cytokine release.
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Fig.3 NKp80 is expressed by certain HCMV-specific CD8 T cells.
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Fig.1 Cell-surface expression of maturation markers after UCBT.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
5D12
Antibody Isotype
IgG1, κ
Application
FC, IP, BL

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Concentration
1.0 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Killer Cell Lectin Like Receptor F1
Introduction
KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]
Entrez Gene ID
51348
UniProt ID
Q9NZS2
Alternative Names
Killer Cell Lectin Like Receptor F1; Killer Cell Lectin-Like Receptor Subfamily F, Member 1; C-Type Lectin Domain Family 5 Member C; Activating Coreceptor NKp80; Lectin-Like Receptor F1; CLEC5C; Killer Cell Lectin-Like Receptor Subfamily F Member 1; NKp80; ML;
Function
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
Biological Process
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Cytoplasmic: 1-38
Helical: 39-59
Extracellular: 60-231
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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