Rat Anti-KLRF1 Recombinant Antibody (CBWJN-0913) (CBMAB-N0050-WJ)

Name: Rat Anti-KLRF1 Recombinant Antibody (CBWJN-0913)
SKU: CBMAB-N0050-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

CBWJN-0913

Application

FC, CyTOF

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Killer Cell Lectin Like Receptor F1

Introduction

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]

Entrez Gene ID

51348

UniProt ID

Q9NZS2

Alternative Names

Killer Cell Lectin Like Receptor F1; Killer Cell Lectin-Like Receptor Subfamily F, Member 1; C-Type Lectin Domain Family 5 Member C; Activating Coreceptor NKp80; Lectin-Like Receptor F1; CLEC5C; Killer Cell Lectin-Like Receptor Subfamily F Member 1; NKp80; ML;

Function

Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.

Biological Process

Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Membrane

Topology

Cytoplasmic: 1-38
Helical: 39-59
Extracellular: 60-231

Mukherjee, N., Ji, N., Tan, X., Chen, C. L., Noel, O. D., Rodriguez‐Padron, M., ... & Svatek, R. S. (2023). KLRF1, a novel marker of CD56bright NK cells, predicts improved survival for patients with locally advanced bladder cancer. Cancer Medicine, 12(7), 8970-8980.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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