KLRF1
KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]
Full Name
Killer Cell Lectin Like Receptor F1
Function
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
Biological Process
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Cytoplasmic: 1-38
Helical: 39-59
Extracellular: 60-231
Helical: 39-59
Extracellular: 60-231
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Anti-KLRF1 antibodies
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Target: KLRF1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBWJN-0230
Application*: F
Target: KLRF1
Host: Recombinant
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0914
Application*: F
Target: KLRF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5D12
Application*: F, IP, B
Target: KLRF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0405
Application*: F
Target: KLRF1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJN-0913
Application*: F, MC
Target: KLRF1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 7D32
Application*: F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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