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Mouse Anti-KRT6C Recombinant Antibody (C11) (CBMAB-K1942-LY)

This product is antibody recognizes KRT6C. The antibody C11 immunoassay techniques such as: ELISA, IHC, IF, EM, IP, WB.
See all KRT6C antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
C11
Antibody Isotype
IgG1
Application
ELISA, IHC, IF, EM, IP, WB

Basic Information

Immunogen
This protein A purified monoclonal antibody was produced by repeated immunizations with purified human cytoskeletal preparations from A431 cells
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1.3 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Keratin 6C
Introduction
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009]
Entrez Gene ID
286887
UniProt ID
P48668
Alternative Names
Keratin 6C; Type-II Keratin Kb12; Keratin 6C; Type II; Cytokeratin-6C; Cytokeratin-6E; Keratin K6h; Keratin 6E; CK-6C;
Biological Process
Intermediate filament cytoskeleton organizationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytosol
Extracellular exosome
Intermediate filament
Keratin filament
Involvement in disease
Palmoplantar keratoderma, non-epidermolytic, focal or diffuse (PPKNEFD):
A dermatological disorder characterized by non-epidermolytic abnormal thickening of the skin on the palms and soles. Diffuse palmoplantar keratoderma is characterized by uniform involvement of the palmoplantar surface, while the focal form consists of localized areas of hyperkeratosis located mainly on pressure points and sites of recurrent friction.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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