Mouse Anti-KYNU Recombinant Antibody (1G2) (CBMAB-K2092-LY)

Shi, Y., Luo, S., Zhai, J., & Chen, Y. (2024). A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1870(2), 166929.

León-Letelier, R. A., Abdel Sater, A. H., Chen, Y., Park, S., Wu, R., Irajizad, E., ... & Fahrmann, J. F. (2023). Kynureninase Upregulation Is a Prominent Feature of NFR2-Activated Cancers and Is Associated with Tumor Immunosuppression and Poor Prognosis. Cancers, 15(3), 834.

Fahrmann, J. F., Tanaka, I., Irajizad, E., Mao, X., Dennison, J. B., Murage, E., ... & Ostrin, E. J. (2022). Mutational activation of the NRF2 pathway upregulates kynureninase resulting in tumor immunosuppression and poor outcome in lung adenocarcinoma. Cancers, 14(10), 2543.

Yang, Q., Hao, J., Chi, M., Wang, Y., Xin, B., Huang, J., ... & Guo, C. (2022). Superior antitumor immunotherapy efficacy of kynureninase modified CAR-T cells through targeting kynurenine metabolism. Oncoimmunology, 11(1), 2055703.

Wang, M., Wang, Y., Zhang, M., Duan, Q., Chen, C., Sun, Q., ... & Shao, Y. (2022). Kynureninase contributes to the pathogenesis of psoriasis through pro‐inflammatory effect. Journal of Cellular Physiology, 237(1), 1044-1056.

Baumgartner, R., Berg, M., Matic, L., Polyzos, K. P., Forteza, M. J., Hjorth, S. A., ... & Ketelhuth, D. F. J. (2021). Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans. Journal of Internal Medicine, 289(1), 53-68.

Jovanovic, F., Candido, K. D., & Knezevic, N. N. (2020). The role of the kynurenine signaling pathway in different chronic pain conditions and potential use of therapeutic agents. International journal of molecular sciences, 21(17), 6045.

Liu, Y., Feng, X., Lai, J., Yi, W., Yang, J., Du, T., ... & Xiao, Y. (2019). A novel role of kynureninase in the growth control of breast cancer cells and its relationships with breast cancer. Journal of cellular and molecular medicine, 23(10), 6700-6707.

Boros, F. A., Bohár, Z., & Vécsei, L. (2018). Genetic alterations affecting the genes encoding the enzymes of the kynurenine pathway and their association with human diseases. Mutation Research/Reviews in Mutation Research, 776, 32-45.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols