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Mouse Anti-LGALS2 Recombinant Antibody (C6) (CBMAB-AP2985LY)

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Datasheet
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
C6
Application
ICC, IHC, IP, WB
Immunogen
Met1~Glu132
Specificity
Human, Pig
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Galectin 2
Entrez Gene ID
Human3957
Pig100217393
UniProt ID
HumanP05162
PigQ29373
Function
This protein binds beta-galactoside. Its physiological function is not yet known.
Biological Process
Cell-cell adhesionManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of inflammatory responseIEA:Ensembl
T cell homeostasisManual Assertion Based On ExperimentIDA:ComplexPortal
Cellular Location
Cytoplasm
Galectin complex

He, S., Ji, Z., Zhang, Q., Zhang, X., Chen, J., Hu, J., ... & Ding, Y. (2023). Investigation of LGALS2 expression in the TCGA database reveals its clinical relevance in breast cancer immunotherapy and drug resistance. Scientific Reports, 13(1), 17445.

Jiang, H., Sun, Q., Huang, Z., Chen, H., Chen, L., & He, X. (2023). LGALS2 and EGR1: markers of endometriosis for predictive, preventive and personalized medicine.

Ji, P., Gong, Y., Jin, M. L., Wu, H. L., Guo, L. W., Pei, Y. C., ... & Shao, Z. M. (2022). In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer. Science Advances, 8(26), eabl8247.

Chetry, M., Bhandari, A., Feng, R., Song, X., Wang, P., & Lin, J. (2022). Overexpression of galectin2 (LGALS2) predicts a better prognosis in human breast cancer. American Journal of Translational Research, 14(4), 2301.

Xu, D., Guo, L., Zhang, S., & Hou, Q. (2022). LGALS2 suppresses the progression of papillary thyroid carcinoma by regulating the PI3K/AKT pathway. Gland Surgery, 11(9), 1518.

Xu, W. D., Wu, Q., He, Y. W., Huang, A. F., Lan, Y. Y., Fu, L., ... & Liu, X. Y. (2021). Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis. Cellular Immunology, 368, 104419.

Li, H., Zhao, L., Lau, Y. S., Zhang, C., & Han, R. (2021). Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth. Oncogene, 40(1), 177-188.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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