Mouse Anti-LGALS2 Recombinant Antibody (CBYCL-259) (CBMAB-L0160-YC)

Provided herein is a Mouse monoclonal antibody against Human LGALS2. The antibody can be used for immunoassay techniques, such as WB, ICC, IHC-P, IHC-Fr, ELISA.
See all LGALS2 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYCL-259

Antibody Isotype

IgG

Application

WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen

Galectin 2

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH7.4, with 0.02% sodium azide, 50% glycerol

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Galectin 2

Introduction

LGALS2 is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction.

Entrez Gene ID

3957

UniProt ID

P05162

Alternative Names

HL14

Function

This protein binds beta-galactoside. Its physiological function is not yet known.

Biological Process

Cell-cell adhesionManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of inflammatory responseIEA:Ensembl
T cell homeostasisManual Assertion Based On ExperimentIDA:ComplexPortal

Cellular Location

Cytoplasm
Galectin complex

References

He, S., Ji, Z., Zhang, Q., Zhang, X., Chen, J., Hu, J., ... & Ding, Y. (2023). Investigation of LGALS2 expression in the TCGA database reveals its clinical relevance in breast cancer immunotherapy and drug resistance. Scientific Reports, 13(1), 17445.

Jiang, H., Sun, Q., Huang, Z., Chen, H., Chen, L., & He, X. (2023). LGALS2 and EGR1: markers of endometriosis for predictive, preventive and personalized medicine.

Ji, P., Gong, Y., Jin, M. L., Wu, H. L., Guo, L. W., Pei, Y. C., ... & Shao, Z. M. (2022). In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer. Science Advances, 8(26), eabl8247.

Chetry, M., Bhandari, A., Feng, R., Song, X., Wang, P., & Lin, J. (2022). Overexpression of galectin2 (LGALS2) predicts a better prognosis in human breast cancer. American Journal of Translational Research, 14(4), 2301.

Xu, D., Guo, L., Zhang, S., & Hou, Q. (2022). LGALS2 suppresses the progression of papillary thyroid carcinoma by regulating the PI3K/AKT pathway. Gland Surgery, 11(9), 1518.

Xu, W. D., Wu, Q., He, Y. W., Huang, A. F., Lan, Y. Y., Fu, L., ... & Liu, X. Y. (2021). Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis. Cellular Immunology, 368, 104419.

Li, H., Zhao, L., Lau, Y. S., Zhang, C., & Han, R. (2021). Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth. Oncogene, 40(1), 177-188.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-LGALS2 Recombinant Antibody (CBYCL-259)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-LGALS2 Recombinant Antibody (1H6)

Mouse Anti-LGALS2 Recombinant Antibody (CBYJL-1504)

Mouse Anti-LGALS2 Recombinant Antibody (6A8)

Mouse Anti-LGALS2 Recombinant Antibody (CBYJL-1505)

Mouse Anti-LGALS2 Recombinant Antibody (13j38)

Human Anti-LGALS2 Recombinant Antibody (H3F3D1)

Mouse Anti-LGALS2 Recombinant Antibody (C6)

Mouse Anti-LGALS2 Recombinant Antibody (CBYCL-260)

Recombinant Mouse Anti-LGALS2 Antibody (CBHb321)

Rat Anti-LGALS2 Recombinant Antibody (747307)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: