Sign in or Register   Sign in or Register
  |  

Mouse Anti-LHB Recombinant Antibody (402) (CBMAB-L1393-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Luteinizing Hormone Beta Polypeptide (LHB). The antibody can be used for immunoassay techniques, such as Immunoassay.
See all LHB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
402
Antibody Isotype
IgG1
Application
Immunoassay

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
LHB
Introduction
LHB is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. Among its related pathways are ERK Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and hormone activity. An important paralog of this gene is CGB7.
Entrez Gene ID
UniProt ID
Alternative Names
CGB4; HH23; LSH-B; LSH-beta
Function
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Biological Process
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Male gonad developmentManual Assertion Based On ExperimentTAS:ProtInc
Progesterone biosynthetic processManual Assertion Based On ExperimentTAS:BHF-UCL
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
Involvement in disease
Hypogonadotropic hypogonadism 23 without anosmia (HH23):
A form of hypogonadotropic hypogonadism, a group of disorders characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. HH23 male patients have normal sexual differentiation, reduced or absent Leydig cells, reduced or absent spermatogenesis, and absence of spontaneous puberty. Female patients exhibit normal pubertal development and menarche, followed by oligomenorrhea and anovulatory secondary amenorrhea.
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-LHB Recombinant Antibody (402)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare