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Mouse Anti-LRP3 Recombinant Antibody (CBYJL-1971) (CBMAB-L2054-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Ldl Receptor Related Protein 3 (LRP3). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all LRP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-1971
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa 671-770 from human LRP3 (NP_002324) with GST tag. MW of the GST tag alone is 26kD.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 671-770

Target

Full Name
LDL receptor related protein 3
Introduction
An important paralog of this gene is LRP12.
Entrez Gene ID
4037
UniProt ID
O75074
Alternative Names
low-density lipoprotein receptor-related protein 3; 105 kDa low-density lipoprotein receptor-related protein; CTD-2540B15.13; LRP-3; hLRp105
Function
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
Biological Process
Negative regulation of fat cell differentiationManual Assertion Based On ExperimentIMP:ARUK-UCL
Negative regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of osteoblast differentiationManual Assertion Based On ExperimentIMP:ARUK-UCL
Receptor-mediated endocytosisManual Assertion Based On ExperimentTAS:ProtInc
Transport across blood-brain barrier1 PublicationNAS:ARUK-UCL
Cellular Location
Membrane
Membrane, coated pit
Topology
Extracellular: 37-496
Helical: 497-517
Cytoplasmic: 518-770
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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