LRP3

An important paralog of this gene is LRP12.

LDL receptor related protein 3

Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.

Negative regulation of fat cell differentiationManual Assertion Based On ExperimentIMP:ARUK-UCL
Negative regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of osteoblast differentiationManual Assertion Based On ExperimentIMP:ARUK-UCL
Receptor-mediated endocytosisManual Assertion Based On ExperimentTAS:ProtInc
Transport across blood-brain barrier1 PublicationNAS:ARUK-UCL

Membrane
Membrane, coated pit

Extracellular: 37-496
Helical: 497-517
Cytoplasmic: 518-770