Mouse Anti-LSM5 Recombinant Antibody (CBYJL-2083) (CBMAB-L2222-YJ)

Name: Mouse Anti-LSM5 Recombinant Antibody (CBYJL-2083)
SKU: CBMAB-L2222-YJ
Rating: 5 (1 reviews)

See all LSM5 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJL-2083

Application

Immunogen

Synthetic peptide corresponding to human LSM5.

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4, 1% BSA

Preservative

0.05% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated

Introduction

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. It plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating formation of the spliceosomal U4/U6 duplex formation in vitro.

Entrez Gene ID

23658

UniProt ID

Q9Y4Y9

Alternative Names

YER146W; U6 snRNA-associated Sm-like protein LSm5; LSM5 U6 small nuclear RNA and mRNA degradation associated; LSM5 homolog, U6 small nuclear RNA associated

Function

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166).
The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).

Biological Process

mRNA catabolic processManual Assertion Based On ExperimentIDA:MGI
mRNA processingManual Assertion Based On ExperimentTAS:ProtInc
mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Response to bacteriumIEA:Ensembl

Cellular Location

Nucleus

Ullah, M. A., Alam, S., Farzana, M., Moin, A. T., Prapty, C. N. B. S., Zohora, U. S., & Rahman, M. S. (2022). Prognostic and therapeutic value of LSM5 gene in human brain cancer Glioma: An omics database exploration approach. Informatics in Medicine Unlocked, 34, 101114.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-LSM5 Recombinant Antibody (CBYJL-2083)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-LSM5 Recombinant Antibody (CBYJL-2084) (CAT#: CBMAB-L2224-YJ)

Mouse Anti-LSM5 Recombinant Antibody (AT25F8) (CAT#: CBMAB-L2223-YJ)

Mouse Anti-LSM5 Recombinant Antibody (CBYJL-2082) (CAT#: CBMAB-L2221-YJ)

Mouse Anti-LSM5 Recombinant Antibody (CBYCL-506) (CAT#: CBMAB-L0407-YC)

Mouse Anti-LSM5 Recombinant Antibody (2525C1a) (CAT#: CBMAB-L2220-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry