Mouse Anti-LST1 Recombinant Antibody (CBYCL-517) (CBMAB-L0418-YC)

Name: Mouse Anti-LST1 Recombinant Antibody (CBYCL-517)
SKU: CBMAB-L0418-YC
Rating: 5 (1 reviews)

See all LST1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYCL-517

Application

ICC, IHC-P, IP, WB

Immunogen

SSEGPDLRGRDKRGT

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH7.4, with 15 mM sodium azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

SSEGPDLRGRDKRGT

More Infomation

Target

Full Name

Leukocyte Specific Transcript 1

Introduction

LST1 is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria.

Entrez Gene ID

7940

UniProt ID

O00453

Alternative Names

B144; D6S49E; LST-1

Function

Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.

Biological Process

Anatomical structure morphogenesis1 PublicationNAS:UniProtKB
Cell morphogenesisIEA:InterPro
Dendrite developmentManual Assertion Based On ExperimentIDA:UniProtKB
Immune response2 PublicationsNAS:UniProtKB
Negative regulation of lymphocyte proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of cell shapeIEA:UniProtKB-KW

Cellular Location

Membrane
Golgi apparatus membrane
Endomembrane system
Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.

Topology

Helical: 8-28

Zhang, J., Cheng, S., Xie, S., Xie, Z., Zhang, H., Wang, F., ... & Jiang, W. (2023). Significance of leukocyte-specific transcript 1 levels in nasal mucosal tissue to predict recurrence of nasal polyps. Brazilian Journal of Otorhinolaryngology, 89, 321-328.

Fabisik, M., Tureckova, J., Pavliuchenko, N., Kralova, J., Balounova, J., Vicikova, K., ... & Brdicka, T. (2021). Regulation of inflammatory response by transmembrane adaptor protein LST1. Frontiers in Immunology, 12, 618332.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-LST1 Recombinant Antibody (CBYCL-517)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-LST1 Recombinant Antibody (LST1/02) (CAT#: CBMAB-L2243-YJ)

Mouse Anti-LST1 Recombinant Antibody (CBYCL-516) (CAT#: CBMAB-L0417-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry