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Mouse Anti-LST1 Recombinant Antibody (LST1/02) (CBMAB-L2243-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Leukocyte Specific Transcript 1 (LST1). The antibody can be used for immunoassay techniques, such as WB, ICC, IF.
See all LST1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
LST1/02
Antibody Isotype
IgG1
Application
WB, ICC, IF

Basic Information

Immunogen
KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1.
Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Leukocyte Specific Transcript 1
Introduction
LST1 is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been observed for this gene.
Entrez Gene ID
Human7940
Mouse16988
UniProt ID
HumanO00453
MouseO08843
Alternative Names
B144; LST-1; D6S49E; leukocyte-specific transcript 1 protein; lymphocyte antigen 117
Function
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Biological Process
Anatomical structure morphogenesis1 PublicationNAS:UniProtKB
Cell morphogenesisIEA:InterPro
Dendrite developmentManual Assertion Based On ExperimentIDA:UniProtKB
Immune response2 PublicationsNAS:UniProtKB
Negative regulation of lymphocyte proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of cell shapeIEA:UniProtKB-KW
Cellular Location
Membrane
Golgi apparatus membrane
Endomembrane system
Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
Topology
Helical: 8-28
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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