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Mouse Anti-LY75 Recombinant Antibody (CBWJC-4126) (CBMAB-C5470WJ)

This product is a Mouse antibody that recognizes LY75. This antibody CBWJC-4126 can be used for immunoassay techniques such as: FC, IHC, WB.
See all LY75 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBWJC-4126
Antibody Isotype
IgG1, κ
Application
FC, IHC, WB

Basic Information

Immunogen
hDEC205-hIgG1Fc protein
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
lymphocyte antigen 75
Introduction
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. Diseases associated with LY75 include Pneumonic Plague and Lipid Pneumonia. Among its related pathways are Dendritic Cells Developmental Lineage Pathway. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is LY75-CD302.
Entrez Gene ID
Human4065
Mouse17076
Rat499800
UniProt ID
HumanO60449
MouseQ60767
RatD3ZQK8
Alternative Names
CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
Function
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity).
Causes reduced proliferation of B-lymphocytes.
Biological Process
EndocytosisIEA:UniProtKB-KW
Immune responseManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 28-1666
Helical: 1667-1691
Cytoplasmic: 1692-1722
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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