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Mouse Anti-MAP1S Recombinant Antibody (CBFYM-0547) (CBMAB-M0676-FY)

This product is mouse antibody that recognizes MAP1S. The antibody CBFYM-0547 can be used for immunoassay techniques such as: ELISA, WB.
See all MAP1S antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-0547
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
microtubule-associated protein 1S
Introduction
MAP1S is a Protein Coding gene. Gene Ontology annotations related to this gene include identical protein binding and actin filament binding. An important paralog of this gene is MAP1B.
Entrez Gene ID
55201
UniProt ID
Q66K74
Alternative Names
Microtubule Associated Protein 1S; Variable Charge Y Chromosome 2-Interacting Protein 1; Microtubule-Associated Protein 8; BPY2-Interacting Protein 1; VCY2-Interacting Protein 1; VCY2IP-1; BPY2IP1; C19orf5
Function
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity).
Biological Process
Apoptotic processIEA:UniProtKB-KW
AutophagyManual Assertion Based On ExperimentTAS:BHF-UCL
AxonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Brain developmentBy SimilarityISS:HGNC-UCL
Dendrite developmentManual Assertion Based On ExperimentIBA:GO_Central
Microtubule bundle formationManual Assertion Based On ExperimentIMP:HGNC-UCL
Microtubule cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Mitochondrion transport along microtubuleManual Assertion Based On ExperimentTAS:HGNC-UCL
Nervous system developmentBy SimilarityISS:HGNC-UCL
Neuron projection morphogenesisManual Assertion Based On ExperimentIEP:HGNC-UCL
Regulation of chromatin disassemblyManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of microtubule depolymerizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Cytoplasm, cytosol
Cytoplasm, cytoskeleton
Cytoplasm, cytoskeleton, spindle
Detected in filopodia-like protrusions and synapses (By similarity).
Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1 isoform A. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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