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Mouse Anti-MAP2K3 Recombinant Antibody (1D10) (CBMAB-A5191-LY)

The product is antibody recognizes MAP2K3. The antibody 1D10 immunoassay techniques such as: WB, ELISA.
Host Species
Mouse
Application
WB, ELISA
Immunogen
MAP2K3 (AAH32478, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG1, κ
Specificity
Human
Clone
1D10
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq]
Alternative Name
MAPKK3; MEK3; MKK3; PRKMK3
Entrez Gene ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-A5191-LY
Conjugates
Size
Price $
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Second antibody and isotype control