Mouse Anti-MEMO1 Recombinant Antibody (A1064) (CBMAB-AP4461LY)

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Basic Information

Host Animal
Mouse
Clone
A1064
Application
Dot blot, ELISA, WB
Immunogen
Recombinant human MEMO1 (1-297aa) purified from E. coli
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
Affinity purity
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Mediator Of Cell Motility 1
Introduction
MEMO1 (Mediator Of Cell Motility 1) is a Protein Coding gene. Among its related pathways are Signaling by ERBB2 and Signaling by GPCR.
Entrez Gene ID
UniProt ID
Alternative Names
Mediator Of Cell Motility 1; Hepatitis C Virus NS5A-Transactivated Protein 7; Mediator Of ErbB2-Driven Cell Motility 1; HCV NS5A-Transactivated Protein 7; C21orf19-Like Protein; NS5ATP7; C2orf4;
Function
01-A0230
Biological Process
Regulation of microtubule-based process Source: UniProtKB
Cellular Location
Cytosol
Nucleus

Ramshekar, A., Wallace-Carrete, C., Zaugg, C. J., Nguyen, J., & Hartnett, M. E. (2023). Elucidating the role of MEMO1 in VEGFR2-triggered signaling in retinal microvascular endothelial cells. Investigative Ophthalmology & Visual Science, 64(8), 1244-1244.

Zhang, X., Walke, G. R., Horvath, I., Kumar, R., Blockhuys, S., Holgersson, S., ... & Wittung-Stafshede, P. (2022). Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro. Proceedings of the National Academy of Sciences, 119(37), e2206905119.

Ren, X., Jing, Y. X., Zhou, Z. W., & Yang, J. W. (2022). Knockdown of circRNA-Memo1 reduces hypoxia/reoxygenation injury in human brain endothelial cells through miRNA-17-5p/SOS1 axis. Molecular Neurobiology, 59(4), 2085-2097.

Shan, K. S., Li, W. W., Ren, W., Kong, S., Peng, L. P., Zhuo, H. Q., & Tian, S. B. (2022). LncRNA cancer susceptibility 20 regulates the metastasis of human gastric cancer cells via the miR-143-5p/MEMO1 molecular axis. World Journal of Gastroenterology, 28(16), 1656.

Trejo-Cerro, O., Massimi, P., Broniarczyk, J., Myers, M., & Banks, L. (2022). Repression of Memo1, a Novel Target of Human Papillomavirus Type 16 E7, Increases Cell Proliferation in Cervical Cancer Cells. Journal of Virology, 96(20), e01229-22.

Schotanus, M. D., & Van Otterloo, E. (2020). Finding MEMO—Emerging Evidence for MEMO1′ s Function in Development and Disease. Genes, 11(11), 1316.

Ding, C., Xi, G., Wang, G., Cui, D., Zhang, B., Wang, H., ... & Wang, J. (2020). Exosomal Circ-MEMO1 promotes the progression and aerobic glycolysis of non-small cell lung cancer through targeting MiR-101-3p/KRAS axis. Frontiers in Genetics, 11, 962.

Xu, K., Shi, J., Mo, D., Yang, Y., Fu, Q., & Luo, Y. (2020). miR-219a-1 inhibits colon cancer cells proliferation and invasion by targeting MEMO1. Cancer biology & therapy, 21(12), 1163-1170.

Moor, M. B., Ramakrishnan, S. K., Legrand, F., Bachtler, M., Koesters, R., Hynes, N. E., ... & Bonny, O. (2020). Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice. PLoS One, 15(7), e0236361.

Nakagawa, N., Plestant, C., Yabuno-Nakagawa, K., Li, J., Lee, J., Huang, C. W., ... & Anton, E. S. (2019). Memo1-mediated tiling of radial glial cells facilitates cerebral cortical development. Neuron, 103(5), 836-852.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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