Mouse Anti-MEOX1 Recombinant Antibody (CBFYM-2067) (CBMAB-M2248-FY)
Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
Multicellular organism development Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Sclerotome development Source: UniProtKB
Somite development Source: UniProtKB
Somite specification Source: Ensembl
Nucleus
Note: Localizes predominantly in the nucleus.
A skeletal disorder characterized by congenital fusion of cervical vertebrae. It is due to a failure in the normal segmentation of vertebrae during the early weeks of fetal development. The clinical triad consists of short neck, low posterior hairline, and limited neck movement.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Mouse Anti-MEOX1 Recombinant Antibody (CBFYM-2066) (CAT#: CBMAB-M2247-FY)
Mouse Anti-MEOX1 (AA 165-252) Recombinant Antibody (CBFYM-2070) (CAT#: CBMAB-M2251-FY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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