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Mouse Anti-MLANA Recombinant Antibody (CBT4065) (V2LY-0625-LY124)


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Tested Data
Mouse Anti-MLANA Recombinant Antibody (CBT4065) (V2LY-0625-LY124) in WB
Mouse Anti-MLANA Recombinant Antibody (CBT4065) (V2LY-0625-LY124) in WB
Mouse Anti-MLANA Recombinant Antibody (CBT4065) (V2LY-0625-LY124) in WB
Mouse Anti-MLANA Recombinant Antibody (CBT4065) (V2LY-0625-LY124) in WB
Mouse Anti-MLANA Recombinant Antibody (CBT4065) (V2LY-0625-LY124) in ELISA
Mouse Anti-MLANA Recombinant Antibody (CBT4065) (V2LY-0625-LY124) in ELISA

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4065
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Purified recombinant fragment of human MLANA (AA: 48-118) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
2315
UniProt ID
Q16655
Function
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Biological Process
Golgi apparatus
trans-Golgi network membrane
Endoplasmic reticulum
Endoplasmic reticulum membrane
Other locations
Melanosome
Note: Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Topology
Helical: 27-47
Cytoplasmic: 48-118
PTM
Acylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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