MLANA
MLANA (Melan-A) is a Protein Coding gene. Diseases associated with MLANA include Melanoma and Microphthalmia. Among its related pathways are NF-kappaB Signaling.
Full Name
Melan-A
Function
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Biological Process
Golgi apparatus
trans-Golgi network membrane
Endoplasmic reticulum
Endoplasmic reticulum membrane
Other locations
Melanosome
Note: Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
trans-Golgi network membrane
Endoplasmic reticulum
Endoplasmic reticulum membrane
Other locations
Melanosome
Note: Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Topology
Helical: 27-47
Cytoplasmic: 48-118
Cytoplasmic: 48-118
PTM
Acylated.
View more
Anti-MLANA antibodies
+ Filters
Loading...
CompareTarget: MLANA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Dog, Human, Mouse
Clone: A1124
Application*: FC, IF, IHC, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: A1123
Application*: FC, IF, IHC, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Horse
Clone: A1122
Application*: FC, IF, IHC, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Dog, Human, Mouse
Clone: A1121
Application*: FC, IF, IHC, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: A1120
Application*: FC, IF, IHC, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Horse
Clone: A1119
Application*: FC, IF, IHC, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Dog, Human, Mouse
Clone: A1118
Application*: FC, IF, IHC, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: A1117
Application*: ELISA, IHC
Target: MLANA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RM333
Application*: IHC, WB
Target: MLANA
Host: Mouse
Specificity: Human
Clone: IHC408
Application*: P, E, IH
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A103
Application*: IH
Target: MLANA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2279
Application*: C, P
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2278
Application*: C, P, IP, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-2277
Application*: F, P, IP, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2276
Application*: WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-2275
Application*: IF, P, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2274
Application*: WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2273
Application*: WB, IH, IF
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Horse, Human
Clone: CBFYM-2272
Application*: IH, IP, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Human
Clone: CBFYM-2270
Application*: IH, IP, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-0654
Application*: IH, IP, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0653
Application*: IH, IP, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Human, Mouse, Rat
Clone: CBFYM-0432
Application*: C, F, IF, IP, P, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBFYM-0431
Application*: C, F, IF, IP, P, WB
Target: MLANA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Horse, Human
Clone: CBFYM-0427
Application*: F, IF, P
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Dog
Clone: CBFYM-0364
Application*: F, IF, WB, C
Target: MLANA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYM-0363
Application*: F, IF, P, WB
Target: MLANA
Host: Mouse
Specificity: Human
Clone: CBFYM-0113
Application*: WB, E
Target: MLANA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4065
Application*: WB
More Infomation
Hot products 
-
Mouse Anti-ARIH1 Recombinant Antibody (C-7) (CBMAB-A3563-YC)
-
Rabbit Anti-ATF4 Recombinant Antibody (D4B8) (CBMAB-A3872-YC)
-
Mouse Anti-ADGRE5 Recombinant Antibody (V2-360335) (CBMAB-C2088-CQ)
-
Mouse Anti-ADGRL2 Recombinant Antibody (V2-58519) (CBMAB-L0166-YJ)
-
Mouse Anti-APOE Recombinant Antibody (A1) (CBMAB-0078CQ)
-
Rabbit Anti-AKT2 (Phosphorylated S474) Recombinant Antibody (V2-556130) (PTM-CBMAB-0605LY)
-
Mouse Anti-BRCA2 Recombinant Antibody (CBYY-1728) (CBMAB-2077-YY)
-
Mouse Anti-ENO1 Recombinant Antibody (CBYC-A950) (CBMAB-A4388-YC)
-
Mouse Anti-BRD3 Recombinant Antibody (CBYY-0801) (CBMAB-0804-YY)
-
Mouse Anti-B2M Recombinant Antibody (CBYY-0050) (CBMAB-0050-YY)
-
Rat Anti-(1-5)-α-L-Arabinan Recombinant Antibody (V2-501861) (CBMAB-XB0003-YC)
-
Mouse Anti-ADIPOR2 Recombinant Antibody (V2-179983) (CBMAB-A1369-YC)
-
Rat Anti-ADAM10 Recombinant Antibody (V2-179741) (CBMAB-A1103-YC)
-
Rat Anti-C5AR1 Recombinant Antibody (8D6) (CBMAB-C9139-LY)
-
Mouse Anti-14-3-3 Pan Recombinant Antibody (V2-9272) (CBMAB-1181-LY)
-
Mouse Anti-APP Recombinant Antibody (DE2B4) (CBMAB-1122-CN)
-
Rabbit Anti-CCN1 Recombinant Antibody (CBWJC-3580) (CBMAB-C4816WJ)
-
Mouse Anti-CIITA Recombinant Antibody (CBLC160-LY) (CBMAB-C10987-LY)
-
Mouse Anti-A2M Recombinant Antibody (V2-178822) (CBMAB-A0036-YC)
-
Mouse Anti-APCS Recombinant Antibody (CBYC-A663) (CBMAB-A3054-YC)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry
