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Mouse Anti-MLLT6 Recombinant Antibody (1B2) (CBMAB-A5520-LY)

The product is antibody recognizes MLLT6. The antibody 1B2 immunoassay techniques such as: WB, ELISA.
See all MLLT6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B2
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
MLLT6 (AAH07237, 1 a.a. ~ 462 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
Entrez Gene ID
4302
UniProt ID
P55198
Alternative Names
AF17; FLJ23480
Biological Process
Negative regulation of histone H3-K79 methylation Source: Ensembl
Negative regulation of urine volume Source: Ensembl
Positive regulation of sodium ion transport Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of transcription, DNA-templated Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Renal potassium excretion Source: Ensembl
Renal sodium excretion Source: Ensembl
Renal water absorption Source: Ensembl
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving MLLT6 is associated with acute leukemias. Translocation t(11;17)(q23;q21) with KMT2A/MLL1. The result is a rogue activator protein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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