MLLT6
MLLT6 (MLLT6, PHD Finger Containing) is a Protein Coding gene. An important paralog of this gene is MLLT10.
Full Name
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
Biological Process
Negative regulation of histone H3-K79 methylation Source: Ensembl
Negative regulation of urine volume Source: Ensembl
Positive regulation of sodium ion transport Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of transcription, DNA-templated Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Renal potassium excretion Source: Ensembl
Renal sodium excretion Source: Ensembl
Renal water absorption Source: Ensembl
Negative regulation of urine volume Source: Ensembl
Positive regulation of sodium ion transport Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of transcription, DNA-templated Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Renal potassium excretion Source: Ensembl
Renal sodium excretion Source: Ensembl
Renal water absorption Source: Ensembl
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving MLLT6 is associated with acute leukemias. Translocation t(11;17)(q23;q21) with KMT2A/MLL1. The result is a rogue activator protein.
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Anti-MLLT6 antibodies
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Target: MLLT6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1B2
Application*: WB, E
Target: MLLT6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2309
Application*: E, WB
Target: MLLT6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2308
Application*: IF, SE, E, WB-Re
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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