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Mouse Anti-MLLT6 (AA 1-462) Recombinant Antibody (CBFYM-2308) (CBMAB-M2493-FY)

This product is mouse antibody that recognizes MLLT6. The antibody CBFYM-2308 can be used for immunoassay techniques such as: IF, S-ELISA, ELISA, WB-Re.
See all MLLT6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2308
Antibody Isotype
IgG1, k
Application
IF, S-ELISA, ELISA, WB-Re

Basic Information

Immunogen
Full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-462

Target

Full Name
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
Introduction
MLLT6 is a Protein Coding gene. An important paralog of this gene is MLLT10.
Entrez Gene ID
4302
UniProt ID
P55198
Alternative Names
MLLT6, PHD Finger Containing; Myeloid/Lymphoid Or Mixed-Lineage Leukemia, Translocated To, 6; Myeloid/Lymphoid Or Mixed-Lineage Leukemia; Translocated To, 6; ALL1-Fused Gene From Chromosome 17 Protein; MLLT6, PHD Finger Domain Containing; Trithorax Homolog
Biological Process
Negative regulation of histone H3-K79 methylation Source: Ensembl
Negative regulation of urine volume Source: Ensembl
Positive regulation of sodium ion transport Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of transcription, DNA-templated Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Renal potassium excretion Source: Ensembl
Renal sodium excretion Source: Ensembl
Renal water absorption Source: Ensembl
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving MLLT6 is associated with acute leukemias. Translocation t(11;17)(q23;q21) with KMT2A/MLL1. The result is a rogue activator protein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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