Sign in or Register   Sign in or Register
  |  

Mouse Anti-MPHOSPH10 (AA 348-458) Recombinant Antibody (CBFYM-2486) (CBMAB-M2673-FY)

This product is mouse antibody that recognizes MPHOSPH10. The antibody CBFYM-2486 can be used for immunoassay techniques such as: IF, WB.
See all MPHOSPH10 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2486
Antibody Isotype
IgG1, k
Application
IF, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 348-458

Target

Full Name
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
Introduction
This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing.
Entrez Gene ID
10199
UniProt ID
O00566
Alternative Names
M-Phase Phosphoprotein 10; Protein Phosphatase 1, Regulatory Subunit 106; U3 Small Nucleolar Ribonucleoprotein; M Phase Phosphoprotein 10; MPP10; M-Phase Phosphoprotein 10 (U3 Small Nucleolar Ribonucleoprotein)
Function
Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
Biological Process
RNA processing Source: UniProtKB
RNA splicing Source: UniProtKB
RNA splicing, via transesterification reactions Source: UniProtKB
rRNA processing Source: UniProtKB-KW
Cellular Location
Nucleus
nucleolus
Other locations
Chromosome
Note: Fibrillar region of the nucleolus (PubMed:9450966). After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966). In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966). The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966).
PTM
Phosphorylated in M (mitotic) phase.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-MPHOSPH10 (AA 348-458) Recombinant Antibody (CBFYM-2486)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare