Mouse Anti-MPHOSPH10 (AA 348-458) Recombinant Antibody (CBFYM-2486) (CBMAB-M2673-FY)

Name: Mouse Anti-MPHOSPH10 (AA 348-458) Recombinant Antibody (CBFYM-2486)
SKU: CBMAB-M2673-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYM-2486

Application

IF, WB

Immunogen

Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG1, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 348-458

More Infomation

Target

Full Name

M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)

Introduction

This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing.

Entrez Gene ID

10199

UniProt ID

O00566

Alternative Names

M-Phase Phosphoprotein 10; Protein Phosphatase 1, Regulatory Subunit 106; U3 Small Nucleolar Ribonucleoprotein; M Phase Phosphoprotein 10; MPP10; M-Phase Phosphoprotein 10 (U3 Small Nucleolar Ribonucleoprotein)

Function

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.

Biological Process

RNA processing Source: UniProtKB
RNA splicing Source: UniProtKB
RNA splicing, via transesterification reactions Source: UniProtKB
rRNA processing Source: UniProtKB-KW

Cellular Location

Nucleus
nucleolus
Other locations
Chromosome
Note: Fibrillar region of the nucleolus (PubMed:9450966). After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966). In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966). The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966).

PTM

Phosphorylated in M (mitotic) phase.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-MPHOSPH10 (AA 348-457) Recombinant Antibody (CBFYM-2487) (CAT#: CBMAB-M2674-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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