Mouse Anti-MPHOSPH10 (AA 348-457) Recombinant Antibody (CBFYM-2487) (CBMAB-M2674-FY)

Name: Mouse Anti-MPHOSPH10 (AA 348-457) Recombinant Antibody (CBFYM-2487)
SKU: CBMAB-M2674-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBFYM-2487

Application

ELISA, WB

Immunogen

Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: NVKKNSDEVK SSFEKRQEKM NEKIASLEKE LLEKKPWQLQ GEVTAQKRPE NSLLEETLHF DHAVRMAPVI TEETTLQLED IIKQRIRDQA WDDVVRKEKP KEDAYEYKKR

Specificity

Human

Antibody Isotype

IgG1, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 348-457

More Infomation

Target

Full Name

M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)

Introduction

This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing.

Entrez Gene ID

10199

UniProt ID

O00566

Alternative Names

M-Phase Phosphoprotein 10; Protein Phosphatase 1, Regulatory Subunit 106; U3 Small Nucleolar Ribonucleoprotein; M Phase Phosphoprotein 10; MPP10; M-Phase Phosphoprotein 10 (U3 Small Nucleolar Ribonucleoprotein)

Function

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.

Biological Process

RNA processing Source: UniProtKB
RNA splicing Source: UniProtKB
RNA splicing, via transesterification reactions Source: UniProtKB
rRNA processing Source: UniProtKB-KW

Cellular Location

Nucleus
nucleolus
Other locations
Chromosome
Note: Fibrillar region of the nucleolus (PubMed:9450966). After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966). In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966). The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966).

PTM

Phosphorylated in M (mitotic) phase.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-MPHOSPH10 (AA 348-458) Recombinant Antibody (CBFYM-2486) (CAT#: CBMAB-M2673-FY)

Isotype control

For research use only. Not intended for any clinical use.

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