Mouse Anti-MT3 Recombinant Antibody (1F11) (CBMAB-A5645-LY)

Mouse

Human

1F11

IgG2b, κ

WB, ELISA

MT3 (AAH13081, 1 a.a. ~ 68 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Human

IgG2b, κ

Monoclonal

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Liquid

> 95% Purity determined by SDS-PAGE.

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

metallothionein 3

GIF; GIFB; GRIF

Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.

Activation of protein kinase B activity Source: UniProtKB
Astrocyte development Source: UniProtKB
Brain development Source: Ensembl
Cadmium ion homeostasis Source: UniProtKB
Cellular lipid catabolic process Source: UniProtKB
Cellular metal ion homeostasis Source: UniProtKB
Cellular response to cadmium ion Source: UniProtKB
Cellular response to copper ion Source: GO_Central
Cellular response to hypoxia Source: UniProtKB
Cellular response to nitric oxide Source: UniProtKB
Cellular response to oxidative stress Source: UniProtKB
Cellular response to zinc ion Source: GO_Central
Cellular zinc ion homeostasis Source: UniProtKB
Cholesterol catabolic process Source: UniProtKB
Detoxification of copper ion Source: GO_Central
Energy reserve metabolic process Source: UniProtKB
ERK1 and ERK2 cascade Source: UniProtKB
Histone modification Source: UniProtKB
Leptin-mediated signaling pathway Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of autophagy Source: UniProtKB
Negative regulation of axon extension Source: UniProtKB
Negative regulation of cell growth Source: UniProtKB
Negative regulation of cysteine-type endopeptidase activity Source: UniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Negative regulation of hydrogen peroxide catabolic process Source: Ensembl
Negative regulation of necrotic cell death Source: UniProtKB
Negative regulation of neuron apoptotic process Source: UniProtKB
Negative regulation of neuron projection development Source: GO_Central
Negative regulation of oxidoreductase activity Source: UniProtKB
Negative regulation of reactive oxygen species metabolic process Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of catalytic activity Source: UniProtKB
Positive regulation of cell death Source: UniProtKB
Positive regulation of ERK1 and ERK2 cascade Source: UniProtKB
Positive regulation of gene expression Source: UniProtKB
Positive regulation of lysosomal membrane permeability Source: UniProtKB
Positive regulation of necrotic cell death Source: UniProtKB
Positive regulation of oxygen metabolic process Source: UniProtKB
Positive regulation of protein phosphorylation Source: UniProtKB
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress Source: UniProtKB
Positive regulation of vascular endothelial growth factor receptor signaling pathway Source: UniProtKB
Protein kinase B signaling Source: UniProtKB
Protein stabilization Source: UniProtKB
Regulation of protein glycosylation Source: UniProtKB
Regulation of response to food Source: UniProtKB
Removal of superoxide radicals Source: UniProtKB
Response to hypoxia Source: UniProtKB
Zinc ion homeostasis Source: UniProtKB
Zinc ion transport Source: UniProtKB

Cytoskeleton
microtubule
Cytosol
Endoplasmic reticulum
rough endoplasmic reticulum
extracellular space
Mitochondrion
mitochondrial outer membrane
Nucleus
Plasma Membrane
Other locations
astrocyte end-foot
axon
cytoplasm
dendritic spine
inclusion body
perinuclear region of cytoplasm
postsynaptic density
ribosome
synaptic vesicle