Sign in or Register   Sign in or Register
  |  

Mouse Anti-NFS1 Recombinant Antibody (CBWJN-0317) (CBMAB-N0338-WJ)

This product is a Mouse antibody that recognizes NFS1. The antibody CBWJN-0317 can be used for immunoassay techniques such as: Dot, WB.
See all NFS1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJN-0317
Antibody Isotype
IgG1
Application
Dot, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NFS1, Cysteine Desulfurase
Introduction
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
Entrez Gene ID
9054
UniProt ID
Q9Y697
Alternative Names
NFS1, Cysteine Desulfurase; Nitrogen Fixation 1 (S. Cerevisiae, Homolog); EC 2.8.1.7; NIFS; NFS1 Nitrogen Fixation 1 Homolog (S. Cerevisiae); Nitrogen-Fixing Bacteria S-Like Protein;
Function
Catalyzes the removal of elemental sulfur from cysteine to produce alanine (PubMed:18650437).
It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor (PubMed:18650437).
Biological Process
[2Fe-2S] cluster assemblyIEA:InterPro
Iron incorporation into metallo-sulfur clusterManual Assertion Based On ExperimentIDA:HGNC-UCL
Iron-sulfur cluster assemblyManual Assertion Based On ExperimentIBA:GO_Central
Mo-molybdopterin cofactor biosynthetic processIEA:UniProtKB-KW
Cellular Location
Isoform Mitochondrial
Mitochondrion
Isoform Cytoplasmic
Cytoplasm
Nucleus
Involvement in disease
Combined oxidative phosphorylation deficiency 52 (COXPD52):
An autosomal recessive mitochondrial disorder with onset in infancy, characterized by lactic acidemia, hypotonia, respiratory chain complex II and III deficiency, multisystem organ failure and abnormal mitochondria.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-NFS1 Recombinant Antibody (CBWJN-0317)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare