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Mouse Anti-NIT2 Recombinant Antibody (1A6) (CBMAB-N2490-WJ)

This product is a Mouse antibody that recognizes NIT2. The antibody 1A6 can be used for immunoassay techniques such as: IHC, IHC-P, WB.
See all NIT2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A6
Antibody Isotype
IgG2a
Application
IHC, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
nitrilase family, member 2
Introduction
Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
Entrez Gene ID
56954
UniProt ID
Q9NQR4
Alternative Names
Nitrilase Family Member 2; Nitrilase Homolog 2; Omega-Amidase NIT2; Epididymis Secretory Sperm Binding Protein Li 8a; Nitrilase Family, Member 2; Nit Protein 2; EC 3.5.1.3; HEL-S-8a;
Function
Has omega-amidase activity (PubMed:22674578, PubMed:19595734).
The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively (PubMed:19595734).
Biological Process
Asparagine metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Glutamine metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Oxaloacetate metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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