Sign in or Register   Sign in or Register
  |  

Mouse Anti-ONECUT1 Recombinant Antibody (CBXO-0565) (CBMAB-O0451-CQ)

This product is a mouse antibody that recognizes ONECUT1. The antibody CBXO-0565 can be used for immunoassay techniques such as: IF, IHC-P, WB.
See all ONECUT1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXO-0565
Antibody Isotype
IgG1
Application
IF, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium Azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ONECUT1
Introduction
This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
3175
UniProt ID
Q9UBC0
Alternative Names
One Cut Homeobox 1; One Cut Domain Family Member 1; HNF6A; HNF-6; HNF6; Hepatocyte Nuclear Factor 6, Alpha; One Cut Domain, Family Member 1; Hepatocyte Nuclear Factor 6
Function
Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.
Biological Process
Anatomical structure morphogenesisIEA:Ensembl
B cell differentiationIEA:Ensembl
Cell fate commitmentIEA:Ensembl
Cilium assemblyIEA:Ensembl
Endocrine pancreas developmentIEA:Ensembl
Endoderm developmentIEA:Ensembl
Epithelial cell developmentIEA:Ensembl
Glucose metabolic processIEA:Ensembl
Liver developmentIEA:Ensembl
Negative regulation of transforming growth factor beta receptor signaling pathwayIEA:Ensembl
Notch signaling pathwayIEA:Ensembl
Positive regulation of cell migrationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIISS:BHF-UCL
Regulation of cell-matrix adhesionIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription, DNA-templated1 PublicationNAS:UniProtKB
Spleen developmentIEA:Ensembl
Cellular Location
Nucleus
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ONECUT1 Recombinant Antibody (CBXO-0565)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare