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Rat Anti-ORM1 Recombinant Antibody (CBXO-0507) (CBMAB-O0569-CQ)

This product is a rat antibody that recognizes ORM1. The antibody CBXO-0507 can be used for immunoassay techniques such as: IP, WB.
See all ORM1 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXO-0507
Antibody Isotype
IgG1
Application
IP, WB

Basic Information

Immunogen
Mouse serum-derived alpha 1-Acid Glycoprotein
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS with 5% trehalose
Preservative
None
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Orosomucoid 1
Introduction
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.
Entrez Gene ID
UniProt ID
Alternative Names
Orosomucoid 1; AGP 1; OMD 1; AGP1; Epididymis Secretory Sperm Binding Protein Li 153w; Alpha-1-Acid Glycoprotein 1
Function
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Biological Process
Acute-phase responseManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of interleukin-6 productionManual Assertion Based On ExperimentIDA:CACAO
Negative regulation of tumor necrosis factor productionManual Assertion Based On ExperimentIDA:CACAO
Positive regulation of interleukin-1 beta productionManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of interleukin-1 productionManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of tumor necrosis factor productionManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of immune system processIEA:InterPro
Cellular Location
Secreted
PTM
N-glycosylated. N-glycan heterogeneity at Asn-33: Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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