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Mouse Anti-PARP4 Recombinant Antibody (2695C5a) (CBMAB-P0823-YC)

Provided herein is a Mouse monoclonal antibody against Human Poly(ADP-Ribose) Polymerase Family Member 4. The antibody can be used for immunoassay techniques, such as Dot.
See all PARP4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2695C5a
Antibody Isotype
IgG1
Application
Dot

Basic Information

Immunogen
Recombinant human Poly (Adp-Ribose) Polymerase Family, Member 4 (Parp4)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4, 1% BSA, 0.05% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Poly(ADP-Ribose) Polymerase Family Member 4
Introduction
PARP4 is poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
Entrez Gene ID
143
UniProt ID
Q9UKK3
Alternative Names
Poly(ADP-Ribose) Polymerase Family Member 4; ADP-Ribosyltransferase (NAD+; Poly (ADP-Ribose) Polymerase)-Like 1; ADP-Ribosyltransferase Diphtheria Toxin-Like 4; Von Willebrand Factor A Domain Containing 5C; PARP-Related/IalphaI-Related H5/Proline-Rich; Vault Poly(ADP-Ribose) Polymerase; 193 KDa Vault Protein; ADPRTL1; PARP-4; ARTD4; PARPL; VPARP; PH5P;
Function
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
Biological Process
Cell deathManual Assertion Based On ExperimentIMP:UniProtKB
Cellular protein modification processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular response to DNA damage stimulus1 PublicationNAS:UniProtKB
DNA repairManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentIMP:UniProtKB
Protein ADP-ribosylation1 PublicationNAS:UniProtKB
Protein mono-ADP-ribosylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of telomerase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Response to xenobiotic stimulus1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Cytoplasm, cytoskeleton, spindle
Also found in the nucleus, associated with mitotic spindles.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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