PARP4

PARP4 is poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
Full Name
Poly(ADP-Ribose) Polymerase Family Member 4
Function
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
Biological Process
Cell deathManual Assertion Based On ExperimentIMP:UniProtKB
Cellular protein modification processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular response to DNA damage stimulus1 PublicationNAS:UniProtKB
DNA repairManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentIMP:UniProtKB
Protein ADP-ribosylation1 PublicationNAS:UniProtKB
Protein mono-ADP-ribosylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of telomerase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Response to xenobiotic stimulus1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Cytoplasm, cytoskeleton, spindle
Also found in the nucleus, associated with mitotic spindles.
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Anti-PARP4 antibodies

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Mouse Anti-PARP4 Recombinant Antibody (2695C5a) (CBMAB-P0823-YC)

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Target: PARP4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2695C5a
Application*: DB
Datasheet SDS

Mouse Anti-PARP4 Recombinant Antibody (CBFYM-3048) (CBMAB-M3244-FY)

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Target: PARP4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-3048
Application*: C, WB
Datasheet SDS

Mouse Anti-PARP4 Recombinant Antibody (CBFYM-3047) (CBMAB-M3243-FY)

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Target: PARP4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-3047
Application*: IH, WB
Datasheet SDS

Mouse Anti-PARP4 (N-terminus) Recombinant Antibody (CBFYM-3046) (CBMAB-M3242-FY)

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Target: PARP4
Host: Mouse
Specificity: Human
Clone: CBFYM-3046
Application*: WB
Datasheet SDS

Mouse Anti-PARP4 (AA 491-494) Recombinant Antibody (CBFYM-3045) (CBMAB-M3241-FY)

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Target: PARP4
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-3045
Application*: WB, IH, IC
Datasheet SDS

Mouse Anti-PARP4 (AA 408-611) Recombinant Antibody (CBFYM-3044) (CBMAB-M3240-FY)

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Target: PARP4
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-3044
Application*: IC, IH, WB
Datasheet SDS

Mouse Anti-PARP4 Recombinant Antibody (CBYC-A1018) (CBMAB-A4651-YC)

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Target: PARP4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYC-A1018
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-PARP4 Recombinant Antibody (P193-10) (CBMAB-V0238-LY)

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Target: PARP4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: P193-10
Application*: C, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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