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Mouse Anti-PDE1A Recombinant Antibody (5C9) (CBMAB-P1185-YC)

Provided herein is a Mouse monoclonal antibody against Human Phosphodiesterase 1A. The antibody can be used for immunoassay techniques, such as WB.
See all PDE1A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5C9
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 259-545

Target

Full Name
Phosphodiesterase 1A
Introduction
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+).
Entrez Gene ID
5136
UniProt ID
P54750
Alternative Names
Phosphodiesterase 1A; Phosphodiesterase 1A, Calmodulin-Dependent; 1 KDa Cam-PDE; EC 3.1.4.17; Cam-PDE 1A; HCAM-1; Calcium/Calmodulin-Dependent 3,5-Cyclic Nucleotide Phosphodiesterase 1A;
Function
Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP.
Biological Process
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
neuronal cell body
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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