Mouse Anti-PDE1A Recombinant Antibody (7D5) (CBMAB-P1187-YC)

Name: Mouse Anti-PDE1A Recombinant Antibody (7D5)
SKU: CBMAB-P1187-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

7D5

Application

WB, IHC

Immunogen

Human recombinant protein fragment corresponding to amino acids 259-545 of human PDE1A (NP_005010) produced in E. coli

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Phosphodiesterase 1A

Introduction

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+).

Entrez Gene ID

5136

UniProt ID

P54750

Alternative Names

Phosphodiesterase 1A; Phosphodiesterase 1A, Calmodulin-Dependent; 1 KDa Cam-PDE; EC 3.1.4.17; Cam-PDE 1A; HCAM-1; Calcium/Calmodulin-Dependent 3,5-Cyclic Nucleotide Phosphodiesterase 1A;

Function

Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP.

Biological Process

Signal transductionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytosol
neuronal cell body

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

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Mouse Anti-PDE1A Recombinant Antibody (5C9) (CAT#: CBMAB-P1185-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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