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Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922)


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Tested Data
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in WB
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in WB
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in WB
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in WB
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in WB
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in WB
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in FC
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in FC
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in IHC
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in IHC
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in IHC
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in IHC
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in ELISA
Mouse Anti-PDE1B Recombinant Antibody (CBT2214) (V2LY-0625-LY922) in ELISA

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
CBT2214
Antibody Isotype
IgG1
Application
IHC, FC

Basic Information

Immunogen
Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. Coli.
Host Species
Mouse
Specificity
Human, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
5153
UniProt ID
Q01064
Function
Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:8855339, PubMed:9419816, PubMed:15260978).
Has a preference for cGMP as a substrate (PubMed:9419816).
Biological Process
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Cellular response to granulocyte macrophage colony-stimulating factor stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Cellular response to macrophage colony-stimulating factor stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Locomotory behaviorIEA:Ensembl
Monocyte differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Regulation of dopamine metabolic processIEA:Ensembl
Regulation of neurotransmitter levelsIEA:Ensembl
Response to amphetamineIEA:Ensembl
Serotonin metabolic processIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Visual learningIEA:Ensembl
Cellular Location
Cytoplasm, cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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