Mouse Anti-PDE4DIP Recombinant Antibody (CBYC-P250) (CBMAB-P1221-YC)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Isoform 13
Participates in microtubule dynamics, promoting microtubule assembly. Depending upon the cell context, may act at the level of the Golgi apparatus or that of the centrosome (PubMed:25217626, PubMed:27666745, PubMed:28814570, PubMed:29162697).
In complex with AKAP9, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745, PubMed:28814570).
In complex with AKAP9, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension from the centrosome to the cell periphery, a crucial process for directed cell migration, mitotic spindle orientation and cell-cycle progression (PubMed:29162697).
Positive regulation of microtubule nucleationIMP:UniProtKB
Protein-containing complex assemblyBy SimilarityISS:UniProtKB
Regulation of Golgi organizationManual Assertion Based On ExperimentIDA:UniProtKB
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Isoform 13
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton
Golgi apparatus
Associated with the microtubule network at the growing distal tip of microtubules (PubMed:29162697).
Targeting to the Golgi apparatus requires AKAP9 (PubMed:25217626).
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
PDE4DIP Matched Antibody Pair (855) (CAT#: APMAB-855LY)
Related Products
Mouse Anti-PDE4DIP Recombinant Antibody (2B5) (CAT#: CBMAB-P1220-YC)
Mouse Anti-PDE4DIP Recombinant Antibody (1C4) (CAT#: CBMAB-P1219-YC)
PDE4DIP Matched Antibody Pair (855) (CAT#: APMAB-855LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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