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Mouse Anti-PDIA5 Recombinant Antibody (3A3) (CBMAB-P1304-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3A3
Antibody Isotype
IgG1, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
PDIA5 (NP_006801, 31-130 aa) partial recombinant protein with GST tag. Immunogen sequence: ERISDPKDLK KLLRTRNNVL VLYSKSEVAA ENHLRLLSTV AQAVKGQGTI CWVDCGDAES RKLCKKMKVD LSPKDKKVEL FHYQDGAFHT EYNRAVTFKS
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 31-130

Target

Full Name
protein disulfide isomerase family A, member 5
Introduction
PDIA5 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein-and non-protein-coding transcript variants.
Entrez Gene ID
10954
UniProt ID
Q14554
Alternative Names
Protein Disulfide Isomerase Family A Member 5; Protein Disulfide Isomerase-Related Protein; Protein Disulfide Isomerase-Associated 5; EC 5.3.4.1; PDIR; Protein Disulfide Isomerase Family A, Member 5; Protein Disulfide-Isomerase A5;
Biological Process
Electron transport chainManual Assertion Based On ExperimentTAS:UniProtKB
Protein foldingManual Assertion Based On ExperimentIDA:FlyBase
Cellular Location
Endoplasmic reticulum lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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