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Mouse Anti-PDIA5 Recombinant Antibody (CBYC-P266) (CBMAB-P1306-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYC-P266
Antibody Isotype
IgG
Application
FC

Basic Information

Immunogen
Synthetic peptide corresponding to the sequence near the C-terminus of rat PDI
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
0.09% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protein disulfide isomerase family A, member 5
Introduction
PDIA5 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein-and non-protein-coding transcript variants.
Entrez Gene ID
Human10954
Mouse72599
Rat360722
UniProt ID
HumanQ14554
MouseQ921X9
RatQ5I0H9
Alternative Names
PDI; PDIR
Biological Process
Electron transport chainManual Assertion Based On ExperimentTAS:UniProtKB
Protein foldingManual Assertion Based On ExperimentIDA:FlyBase
Cellular Location
Endoplasmic reticulum lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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