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PDIA5

PDIA5 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein-and non-protein-coding transcript variants.

Full Name

protein disulfide isomerase family A, member 5

Biological Process

Electron transport chainManual Assertion Based On ExperimentTAS:UniProtKB
Protein foldingManual Assertion Based On ExperimentIDA:FlyBase

Cellular Location

Endoplasmic reticulum lumen

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Anti-PDIA5 antibodies

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Mouse Anti-PDIA5 Recombinant Antibody (CBYC-P266) (CBMAB-P1306-YC)

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Target: PDIA5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBYC-P266

Application*: F

Mouse Anti-PDIA5 Recombinant Antibody (CBYC-P265) (CBMAB-P1305-YC)

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Target: PDIA5

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYC-P265

Application*: E, IC, WB

Mouse Anti-PDIA5 Recombinant Antibody (3A3) (CBMAB-P1304-YC)

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Target: PDIA5

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3A3

Application*: E, IF, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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