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Recombinant Mouse Anti-PDS5A Recombinant Antibody (AF5-21-7) (CBMAB-XB0918-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
AF5-21-7
Application
IHC, IF, IP, WB

Basic Information

Specificity
Human, Mouse
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PDS5 Cohesin Associated Factor A
Introduction
PDS5A binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis.
Entrez Gene ID
Human23244
Mouse71521
UniProt ID
HumanQ29RF7
MouseQ6A026
Alternative Names
PDS5 Cohesin Associated Factor A; Cell Proliferation-Inducing Gene 54 Protein; Sister Chromatid Cohesion Protein 112; SCC-112; PDS5, Regulator Of Cohesion Maintenance, Homolog A (S. Cerevisiae); PDS5, Regulator Of Cohesion Maintenance, Homolog A;
Function
Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Biological Process
Cell divisionIEA:UniProtKB-KW
DNA repairManual Assertion Based On ExperimentIBA:GO_Central
Mitotic sister chromatid cohesionManual Assertion Based On ExperimentIPI:UniProtKB
Negative regulation of DNA replicationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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