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Mouse Anti-PDS5A Recombinant Antibody (CBXS-2002) (CBMAB-S4769-CQ)

This product is a mouse antibody that recognizes PDS5A. The antibody CBXS-2002 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all PDS5A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2002
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PDS5 Cohesin Associated Factor A
Introduction
The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
23244
UniProt ID
Q29RF7
Alternative Names
PDS5 Cohesin Associated Factor A; Cell Proliferation-Inducing Gene 54 Protein; Sister Chromatid Cohesion Protein 112; SCC-112; PDS5, Regulator Of Cohesion Maintenance, Homolog A (S. Cerevisiae); PDS5, Regulator Of Cohesion Maintenance, Homolog A;
Function
Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Biological Process
Cell divisionIEA:UniProtKB-KW
DNA repairManual Assertion Based On ExperimentIBA:GO_Central
Mitotic sister chromatid cohesionManual Assertion Based On ExperimentIPI:UniProtKB
Negative regulation of DNA replicationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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