Mouse Anti-PGP Recombinant Antibody (5F220) (CBMAB-P1602-YC)

Name: Mouse Anti-PGP Recombinant Antibody (5F220)
SKU: CBMAB-P1602-YC
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

5F220

Application

FC, IHC, WB

Immunogen

Human P-gp

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Phosphoglycolate Phosphatase

Introduction

PGP has broad expression in testis (RPKM 12.7), brain (RPKM 7.6) and 25 other tissues.

Entrez Gene ID

283871

UniProt ID

A6NDG6

Alternative Names

Phosphoglycolate Phosphatase; Aspartate-Based Ubiquitous Mg(2+)-Dependent Phosphatase; G3PP; AUM; Glycerol-3-Phosphate Phosphatase; EC 3.1.3.18;

Function

Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581).
In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).

Biological Process

DephosphorylationISS:UniProtKB
Glycerol biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Glycerophospholipid metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of gluconeogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-tyrosine dephosphorylationISS:UniProtKB

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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