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PGP

PGP has broad expression in testis (RPKM 12.7), brain (RPKM 7.6) and 25 other tissues.

Full Name

Phosphoglycolate Phosphatase

Function

Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581).
In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).

Biological Process

DephosphorylationISS:UniProtKB
Glycerol biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Glycerophospholipid metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of gluconeogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-tyrosine dephosphorylationISS:UniProtKB

Cellular Location

Cytoplasm

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Anti-PGP antibodies

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Mouse Anti-PGP Recombinant Antibody (CBYC-P336) (CBMAB-P1604-YC)

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Target: PGP

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBYC-P336

Application*: WB, IH, IF, IC, IP

Mouse Anti-PGP Recombinant Antibody (6D655) (CBMAB-P1603-YC)

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Target: PGP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Hamster

Clone: 6D655

Application*: F, IC, IH

Mouse Anti-PGP Recombinant Antibody (5F220) (CBMAB-P1602-YC)

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Target: PGP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5F220

Application*: F, IH, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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