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Mouse Anti-PGP Recombinant Antibody (CBYC-P336) (CBMAB-P1604-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYC-P336
Antibody Isotype
IgG
Application
WB, IHC, IF, ICC, IP

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Phosphoglycolate Phosphatase
Introduction
PGP has broad expression in testis (RPKM 12.7), brain (RPKM 7.6) and 25 other tissues.
Entrez Gene ID
Human283871
Mouse67078
Rat287115
UniProt ID
HumanA6NDG6
MouseQ8CHP8
RatD3ZDK7
Alternative Names
Phosphoglycolate Phosphatase; Aspartate-Based Ubiquitous Mg(2+)-Dependent Phosphatase; G3PP; AUM; Glycerol-3-Phosphate Phosphatase; EC 3.1.3.18;
Function
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581).
In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).
Biological Process
DephosphorylationISS:UniProtKB
Glycerol biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Glycerophospholipid metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of gluconeogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-tyrosine dephosphorylationISS:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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